Dr. Catherine Wilfert joined the faculty of the Duke University Medical Center in 1971, researching virology. When the AIDS epidemic began, Dr. Wilfert began working towards the eradication of pediatric AIDS, founding the Pediatric Infectious Disease Clinic at Duke. Her discovery that the anti-retroviral drug AZT could reduce the rate of mother-to-infant AIDS transmission reduced pediatric AIDS in the United States by 75 percent and was applied around the world.